Hardware
| Multi-Angle Light Scattering (MALS) | |
 18 angle MALS light scattering instrument for absolute molecular weight, size, & conformation of macromolecules in solution. |
 3 angle MALS light scattering instrument for absolute molecular weight, size, & conformation of macromolecules in solution. |
| Dynamic Light Scattering Technologies (DLS aka QELS or PCS) | ||
 Stand alone Dynamic Light Scattering instrument for measuring the sizes of proteins, nanoparticles, vesicles, and more! |
 Quasi-elastic light scattering (QELS or DLS) which interfaces to the MALS instruments for on-line size measurements of proteins, nanoparticles, etc. |
 Automated high throughput dynamic light scattering technology to measure the sizes of proteins, nanoparticles, etc. in 96 or 384 or 1536 well plates. |
| Viscometer | Field Flow Fractionation | |
 Refractive index detector to measure the concentration of an analyte in solution, the dn/dc, and the absolute refractive index of the solution. |
 On-line differential viscometer to measure the intrinsic viscosity and Mark Houwink-Sakurada (MHS) parameters of polymers. |
 Asymmetric flow Field Flow Fractionation connects to the MALS systems to separate and characterize proteins, nanopartices, polymers etc. |
| Automated Composition Gradients | ||
 Macromolecular interactions such as protein-protein association, aggregation, and kinetics may be characterized via Composition-Gradient MALS. Calypso automates sample preparation, delivery to detectors, data acquisition and analysis for measuring equilibrium association constants of reversible self- and hetero-associations, reaction rates, virial coefficients and dn/dc. |
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Wyatt Technology is the world leader in providing the most advanced macromolecular and nanoparticle characterization tools. These instruments and software may be used to determine the absolute molecular weight and or size of macromolecules and nanoparticles and include: multi-angle light scattering, dynamic light scattering, high through-put dynamic light scattering, field flow fractionation, refractive index and viscometry detection.